Clean the Floor of the Cage

Step1

Combine vinegar and water in the spray bottle.

Step2

Spray the floor of the cage liberally with the water/vinegar solution. Guinea pig urine is a base (and can have an ammonia-like odor), and the acid in the vinegar acts as a neutralizer for the odor.

Step3

Wipe the cage down with a damp sponge. Dry completely with a paper towel.

Source: E-How